Renal Replacement Therapy in Sepsis

A review

The lecture duration is 18min.

0.5 CPD Points, 0.5 CEUs, 0.5 CME credits approval pending.
Accredited by CPDUK, CBRN and Provider Pending.

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Prof. Rinaldo Bellomo
Director of Intensive Care Research at the Austin Hospital; Professor of Intensive Care Medicine, University of Melbourne; Honorary Professor, Monash University, The George Institute of Global Health, University of Sydney, and Honorary Fellow, Florey Institute of Physiology, Melbourne; Co-director of the Australian and New Zealand Intensive Care Research Centre, Monash University School of Public Health and Preventive Medicine; and an NHMRC Practitioner Fellow
Lecture Summary

Accepted indications for commencing RRT to support kidney function during SA-AKI are consistent with other causes of AKI. While earlier RRT initiation for SA-AKI has been considered for fluid and solute control and to prevent multi-organ dysfunction (MOD), no clear benefit for earlier initiation has been demonstrated. Of the recent randomized controlled trials focused on the timing of initiation of RRT in critically ill AKI patients, the IDEAL-ICU study is the only one focused on SA-AKI and demonstrated that earlier initiation of RRT had no significant benefit on survival compared to “standard” initiation although a significant number in the “delayed” group were not treated with RRT, due to spontaneous renal recovery. Initiation of RRT in both septic and non-septic conditions should be based on clinical assessment and goals of RRT for kidney support, not just creatinine levels and oliguria.

Target Audience

Emergency Medicine Doctors
Emergency Medicine Nurses
Paramedics
Rural GP's

Learning Objectives:

Upon completion of this activity, you should be able to:

  • Importance of dose of RRT and related trials
  • Importance of timing of RRT and related trials
  • Importance of modality and related knowledge

None.