Vasoactive Drugs: Facts and Fallacies

A review of the evidence

The lecture duration is 41min.

0.75 CPD Points, 0.75 CEUs, 0.75 AMA PRA Category 1 Credits.
Accredited by CPDUK, CBRN and EB Medicine.

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John Myburgh
Professor of Intensive Care Medicine, The George Institute, Australia
Lecture Summary

Physiological facts: Haemodynamics are complex and represent a teleological neurohormonal response to stress. Defence of MAP represents the balance between the afferent and efferent circulations and the compliance of the system. Monitoring is an aid to an overall assessment that must be considered within the clinical context and patient’s trajectory of illness. Pharmacological facts: Catecholamines are hormones that are administered to augment inadequate endogenous responses. Synthetic catecholamines have no established role in clinical practice. Neurohormonal supplementation strategies have limited roles and should be confined to indications established from RCTs. Non-catecholamine inodilators have not been demonstrated to improve patient-centred outcomes in critically ill patients.

Target Audience

Critical Care Doctors
Experienced or advanced Critical Care Nurses

Learning Objectives:

Upon completion of this activity, you should be able to:

  • Understand the integration of cardiovascular physiology and pharmacology of drugs used to support the failing circulation
  • Recognise the limitations of derived and surrogate indices in determining haemodynamic function
  • Understand the role and application of endogenous catecholamine infusions in supporting the failing circulation
  • Understand the limitations of the use of synthetic vasoactive drugs in critically ill patients

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of EB Medicine and Continulus. EB Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

EB Medicine designates this internet-enduring material for a maximum of .75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Needs Assessment

The need for this educational activity was determined by surveys of the target audience and experts in the specialty. Further assessment was provided by examining the topics of recently published evidence-based medicine reviews, national clinical guidelines, and specialty society recommendations, as well as suggestions from evaluations of previous learning programs to determine practice gaps.

CME Faculty Disclosure

It is the policy of EB Medicine to ensure objectivity, balance, independence, transparency, and scientific rigor in all CME-sponsored educational activities. All faculty participating in the planning or implementation of a sponsored activity are expected to disclose to the audience any relevant financial relationships and to assist in resolving any conflict of interest that may arise from the relationship. In compliance with all ACCME accreditation requirements and policies, all faculty for this CME activity were asked to complete a full disclosure statement. The speaker did not report any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) discussed in this educational presentation.

Earning Credit

In order to earn CME credit, the participant must take the pre-test, watch the course, take the CME post-test, and complete the post-test evaluation.

Hardware/Software Requirements

Online learners will need a computer or web-enabled device to access the podcast, additional learning materials, and CME test.

Commercial Support

This activity received no commercial support.