What clinicians should know about inflammation in sepsis

A refresher on the pathophysiology of inflammation

The lecture duration is 57min.

1 CPD Point, 1 CEU, 1 CME credit approval pending.
Accredited by CPDUK, CBRN and Provider Pending.

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Didier Payen
Professor of Anaesthesiology and Intensive Care at the University Paris 7, France
Lecture Summary

Inflammation is the cornerstone of almost all life-threatening conditions motivating ICU admission. This lecture will try to give a picture of the inflammatory response putting on scene the major actors of the play. Integrating their interactions, the sepsis will be used as an example to demonstrate the kinetic of inflammation and the potential to intervene with drugs to modulate the host response facing pathogens. The recent SARS-Cov-2 pandemic is a perfect example of the role of the host response to the virus as a key determinant of the clinical presentation, acquired specific immunity, and strategy for vaccine development.

Target Audience

Critical Care Doctors
Experienced or advanced Critical Care Nurses

Learning Objectives:

Upon completion of this activity, you should be able to:

  • Describe the global picture of inflammation
  • Know the different components of inflammation and immune factors
  • Understand the kinetics of the immune response after the hit
  • Being able to propose some important routine and more specific biomarkers to become classic in the near future
  • Understand the potential targets for immune modulation