Lecture Summary

Inflammation is the cornerstone of almost all life-threatening conditions motivating ICU admission. This lecture will try to give a picture of the inflammatory response putting on scene the major actors of the play. Integrating their interactions, the sepsis will be used as an example to demonstrate the kinetic of inflammation and the potential to intervene with drugs to modulate the host response facing pathogens. The recent SARS-Cov-2 pandemic is a perfect example of the role of the host response to the virus as a key determinant of the clinical presentation, acquired specific immunity, and strategy for vaccine development.

Target Audience

Critical Care Doctors
Experienced or advanced Critical Care Nurses

Learning Objectives:

Upon completion of this activity, you should be able to:

• Describe the global picture of inflammation
• Know the different components of inflammation and immune factors
• Understand the kinetics of the immune response after the hit
• Being able to propose some important routine and more specific biomarkers to become classic in the near future
• Understand the potential targets for immune modulation

Accreditation

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of EB Medicine and Continulus. EB Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

EB Medicine designates this internet-enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Needs Assessment

The need for this educational activity was determined by surveys of the target audience and experts in the specialty. Further assessment was provided by examining the topics of recently published evidence-based medicine reviews, national clinical guidelines, and specialty society recommendations, as well as suggestions from evaluations of previous learning programs to determine practice gaps.

CME Faculty Disclosure

It is the policy of EB Medicine to ensure objectivity, balance, independence, transparency, and scientific rigor in all CME-sponsored educational activities. All faculty participating in the planning or implementation of a sponsored activity are expected to disclose to the audience any relevant financial relationships and to assist in resolving any conflict of interest that may arise from the relationship. In compliance with all ACCME accreditation requirements and policies, all faculty for this CME activity were asked to complete a full disclosure statement. The speaker did not report any relevant financial interest or other relationship with the manufacturer(s) of any commercial product(s) discussed in this educational presentation.

Earning Credit

In order to earn CME credit, the participant must take the pre-test, watch the course, take the CME post-test, and complete the post-test evaluation.

Hardware/Software Requirements

Online learners will need a computer or web-enabled device to access the podcast, additional learning materials, and CME test.

Commercial Support

This activity received no commercial support.

Inflammation: COVID-19 vs Sepsis

A review of the literature

Critical Care Medicine / Sepsis

Inflammation: COVID-19 vs Sepsis

A review of the literature

Emergency Medicine / Sepsis